Medication Safety Data Sheet (MSDS)
Arsenic trioxide
First Aid Measures
In Case of Inhalation: Remove to fresh air and keep patient at rest. Seek medical attention immediately.
In Case of Eye Contact: Immediately wash skin with soap and plenty of water for at least 20 minutes. Remove contaminated clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
In Case of Skin Contact: Immediately wash skin with soap and plenty of water for at least 15 minutes. Remove contaminated clothing. Get medical attention if symptoms occur. Wash clothing before reuse.
In Case of Ingestion: Wash out mouth with water provided person is conscious. Never give anything by mouth to an unconscious person. Get medical attention. Do NOT induce vomiting unless directed to do so by medical personnel.
Nurses : Withdrawing an injectable dose prior to administration
Closed systems transfer device (CSTD) must be used for administration of antineoplastic Hazardous Drug s (HD)when the dosage form allows. CSTDs known to be physically or chemically incompatible with a specific HD must not be used for that HD.
Two pairs of chemotherapy gloves are required for administering antineoplastic HDs. Gowns shown to resist permeability by HDs are required when administering injectable antineoplastic HDs.
NIOSH Table 5 guidance:
- Double chemotherapy gloves
- Protective gown
- Eye/face protection, if liquid that could splash
Cleaning Up a Spill
All personnel who may be required to clean up a spill of HDs must receive proper training in spill management the use of PPE and NIOSH-certified respirators. Spills must be contained and cleaned immediately only by qualified personnel with appropriate PPE. Spill kits containing all of the materials needed to clean HD spills must be readily available in all areas where HDs are routinely handled. Signs must be available for restricting access to the spill area. All spill materials must be disposed of as hazardous waste.
NIOSH Table 5 guidance recommends:
• Double chemotherapy gloves
• Protective gown
• Eye/Face protection
• Respiratory protection
