الأربعاء، 28 يوليو 2021

Azacitidine

    

Medication Safety Data Sheet  (MSDS)

Azacitidine



First Aid Measures

In Case of Inhalation: Move to fresh air. Call a physician if symptoms develop or persist.

In Case of Eye Contact: In case of contact with the product solution, flush eyes with water for at least 15 minutes. Seek medical attention immediately.


In Case of Skin Contact: If the formulation comes in contact with skin and clothing, remove contaminated clothing and wash thoroughly with running water for at least 15 minutes. Use soap if available. Seek medical attention if irritation develops.



In Case of Ingestion: Seek medical attention immediately. Never give anything by mouth to an unconscious person. 

Nurses : Withdrawing an injectable dose prior to administration


Closed systems transfer device (CSTD) must be used for administration of antineoplastic Hazardous  Drug s (HD)when the dosage form allows. CSTDs known to be physically or chemically incompatible with a specific HD must not be used for that HD. 

Two pairs of chemotherapy gloves are required for administering antineoplastic HDs. Gowns shown to resist permeability by HDs are required when administering injectable antineoplastic HDs. 

NIOSH Table 5 guidance:
  1. Double chemotherapy gloves
  2. Protective gown
  3. Eye/face protection, if liquid that could splash

Cleaning Up  a Spill 


All personnel who may be required to clean up a spill of HDs must receive proper training in spill management the use of PPE and NIOSH-certified respirators.  Spills must be contained and cleaned immediately only by qualified personnel with appropriate PPE. Spill kits containing all of the materials needed to clean HD spills must be readily available in all areas where HDs are routinely handled. Signs must be available for restricting access to the spill area. All spill materials must be disposed of as hazardous waste. 

NIOSH Table 5 guidance recommends:

Double chemotherapy gloves
Protective gown
Eye/Face protection
Respiratory protection